Featured Publications

Ast T*, Meisel JD*, Patra S, …, Ruvkun G, Barondeau DP, Mootha VK. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019

Meisel JD, Miranda M, Skinner OS, …, Jourdain AA, Ruvkun G*, Mootha VK*. Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism. Cell. 2024

All Publications

Meisel JD, Wiesenthal PP, Mootha VK*, Ruvkun G*. CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene. Current Biology. 2024 Jun 17;34(12):2728-2738.e6. doi: 10.1016/j.cub.2024.04.079. PMID: 38810637; PMCID: PMC11265314.
Featured in News & Views: RNA: De-silencing to the rescue

Lee H, Boor SA, Hilbert ZA, Meisel JD, Park J, Wang Y, McKeown R, Fischer SEJ, Andersen EC, Kim DH. Genetic variants that modify neuroendocrine gene expression and foraging behavior of C. elegans. Science Advances. 2024 Jun 14;10(24):eadk9481. doi: 10.1126/sciadv.adk9481. PMID: 38865452; PMCID: PMC11168454.

Meisel JD, Miranda M, Skinner OS, Wiesenthal PP, Wellner SM, Jourdain AA, Ruvkun G*, Mootha VK*. Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism. Cell. 2024 Feb 1;187(3):659-675.e18. doi: 10.1016/j.cell.2023.12.010. PMID: 38215760; PMCID: PMC10919891.

Boor SA, Meisel JD, Kim DH. Neuroendocrine gene expression coupling of interoceptive bacterial food cues to foraging behavior of C. elegans. Elife. 2024 Jan 17;12. doi: 10.7554/eLife.91120. PMID: 38231572; PMCID: PMC10945577.

Rath S, Sharma R, Gupta R, Ast T, Chan C, Durham TJ, Goodman RP, Grabarek Z, Haas ME, Hung WHW, Joshi PR, Jourdain AA, Kim SH, Kotrys AV, Lam SS, McCoy JG, Meisel JD, Miranda M, Panda A, Patgiri A, Rogers R, Sadre S, Shah H, Skinner OS, To TL, Walker MA, Wang H, Ward PS, Wengrod J, Yuan CC, Calvo SE, Mootha VK. MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations. Nucleic Acids Research. 2021 Jan 8;49(D1):D1541-D1547. doi: 10.1093/nar/gkaa1011. PMID: 33174596; PMCID: PMC7778944.

Park J, Meisel JD, Kim DH. Immediate activation of chemosensory neuron gene expression by bacterial metabolites is selectively induced by distinct cyclic GMP-dependent pathways in Caenorhabditis elegans. PLoS Genetics. 2020 Aug;16(8):e1008505. doi: 10.1371/journal.pgen.1008505. PMID: 32776934; PMCID: PMC7416920.

Ast T*, Meisel JD*, Patra S, Wang H, Grange RMH, Kim SH, Calvo SE, Orefice LL, Nagashima F, Ichinose F, Zapol WM, Ruvkun G, Barondeau DP, Mootha VK. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019 May 30;177(6):1507-1521.e16. doi: 10.1016/j.cell.2019.03.045. PMID: 31031004; PMCID: PMC6911770.

Kamer KJ, Sancak Y, Fomina Y, Meisel JD, Chaudhuri D, Grabarek Z, Mootha VK. MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca(2+) and Mn(2+). Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E7960-E7969. doi: 10.1073/pnas.1807811115. PMID: 30082385; PMCID: PMC6112746.

Meisel JD, Kim DH. Inhibition of Lithium-Sensitive Phosphatase BPNT-1 Causes Selective Neuronal Dysfunction in C. elegans. Current Biology. 2016 Jul 25;26(14):1922-8. doi: 10.1016/j.cub.2016.05.050. PMID: 27397889; PMCID: PMC4961587.
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Berube PM, Biller SJ, Kent AG, Berta-Thompson JW, Roggensack SE, Roache-Johnson KH, Ackerman M, Moore LR, Meisel JD, Sher D, Thompson LR, Campbell L, Martiny AC, Chisholm SW. Physiology and evolution of nitrate acquisition in Prochlorococcus. ISME J. 2015 May;9(5):1195-207. doi: 10.1038/ismej.2014.211. PMID: 25350156; PMCID: PMC4409163.

Meisel JD, Panda O, Mahanti P, Schroeder FC, Kim DH. Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans. Cell. 2014 Oct 9;159(2):267-80. doi: 10.1016/j.cell.2014.09.011. PubMed PMID: 25303524; PubMed Central PMCID: PMC4194030.

Meisel JD, Kim DH. Behavioral avoidance of pathogenic bacteria by Caenorhabditis elegans. Trends Immunol. 2014 Oct;35(10):465-70. doi: 10.1016/j.it.2014.08.008. PMID: 25240986.

Scimone ML, Meisel J, Reddien PW. The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterranea. Development. 2010 Apr;137(8):1231-41. doi: 10.1242/dev.042051. PMID: 20223763; PMCID: PMC2847463.

Joshua Meisel Bibliography: MyNCBI - Google Scholar